Endocrine Abstracts

One possible route for treating type 1 diabetes is through an induced augmentation of beta cell mass. Some success has been achieved in recent years using islet grafts into the liver but at present the main limitation to the wider application of this technique is the limited supply of islets from human organ donors. To overcome this problem, alternative sources of β-cells need to be found. One approach is via transdifferentiation, or the conversion of one cell type...